Searchable abstracts of presentations at key conferences in endocrinology

ea0032p364 | Diabetes | ECE2013

Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet

Beiroa Daniel , Amparo Romero-Pico , Carmen Langa , Carmelo Bernabeu , Miguel Lopez , Lopez-Novoa Jose M , Ruben Nogueiras , Carlos Dieguez

Introduction: Endoglin is a transmembrane auxiliary receptor for transforming growth factor-β (TGF-β) that is predominantly expressed on proliferating endothelial cells. It plays a wide range of physiological roles but its importance on energy balance or insulin sensitivity has been unexplored.Material and methods: Heterozygous deficient mice (HZ) were fed standard chow or high fat diet during 16 weeks. Blood glucose levels were measured after ...